Bullshit. This hits home with me. You absolutely don't know what you are talking about as it pertains to faulty breast implants. But it s consistent with most if your posts.
Risk of Connective Tissue Disorders among Breast Implant Patients
https://doi.org/10.1093/aje/kwh272
Published:
01 October 2004
Issue Section:
ORIGINAL CONTRIBUTIONS
Received for publication December 12, 2003; accepted for publication April 15, 2004.
Considerable controversy has surrounded the long-term safety of silicone breast implants. Concerns regarding cancer risk have centered around breast cancer, hematopoietic malignancies, and sarcomas (
brinton@nih.gov).
TABLE 1.
Relative risk of self-reported connective tissue disorders and other conditions among patients with breast implants in comparison with other plastic surgery patients, southeastern United States, 1960–1996
Condition* No. of implant patients (
n = 7,234) (87,199 person-years) No. of comparison patients (
n = 2,138) (23,724 person-years) Relative risk† 95% confidence interval
Connective tissue disorders 351 62 2.0 1.5, 2.8
Rheumatoid arthritis 258 49 1.9 1.4, 2.7
Scleroderma 23 3 3.0 0.8, 10.9
Systemic lupus erythematosus 72 10 2.1 1.1, 4.2
Sjögren’s syndrome 43 2 11.7 2.5, 54.9
Other conditions
Other arthritis 724 201 1.3 1.1, 1.6
Raynaud’s phenomenon 97 10 2.6 1.3, 5.1
Fibromyalgia 311 57 1.3 0.9, 1.7
Vasculitis 21 4 1.4 0.5, 4.6
Chronic fatigue syndrome 246 27 2.4 1.6, 3.6
Multiple sclerosis 26 5 0.7 0.2, 1.9
Other disorders 202 24 2.5 1.6, 3.9
* Conditions are not mutually exclusive.
† Adjusted for age at follow-up (5-year intervals through age 85 years), calendar period of follow-up (1960–1964, …, 1990–1994, 1995–1996), and race (White or Black).
TABLE 2.
Relative risk* of self-reported connective tissue disorders and other conditions among patients with breast implants in comparison with other plastic surgery patients, by period of diagnosis, southeastern United States, 1960–1996
Condition Period of diagnosis
Before 1992 During or after 1992
No. of cases observed† RR‡ 95% CI‡ No. of cases observed† RR 95% CI
Connective tissue disorders 185 1.7 1.2, 2.5 166 2.6 1.6, 4.1
Rheumatoid arthritis 145 1.9 1.2, 3.0 113 2.0 1.2, 3.3
Scleroderma 13 2.6 0.5, 13.6 10 2.3 0.3, 18.2
Systemic lupus erythematosus 29 0.9 0.4, 2.1 43 5.9 1.4, 24.6
Sjögren’s syndrome 12 12.1 1.1, 134 31 10.1 1.4, 75.2
Other conditions
Other arthritis 397 1.3 1.0, 1.6 327 1.3 1.0, 1.6
Raynaud’s phenomenon 47 1.8 0.7, 4.8 50 3.1 1.2, 8.1
Fibromyalgia 156 0.9 0.6, 1.4 155 1.9 1.2, 3.0
Vasculitis 10 2.6 0.3, 22.0 11 1.3 0.4, 5.1
Chronic fatigue syndrome 123 1.9 1.1, 3.2 123 3.3 1.7, 6.3
Multiple sclerosis 10 0.6 0.2, 2.2 6 0.6 0.1, 3.1
Other disorders 82 1.4 0.8, 2.6 120 3.6 1.9, 7.0
* Adjusted for age at follow-up (5-year intervals through age 85 years), calendar period of follow-up (1960–1964, …, 1990–1994, 1995–1996), and race (White or Black).
† Number of breast implant patients with the disorder.
‡ RR, relative risk; CI, confidence interval.
TABLE 3.
Relative risk* of self-reported connective tissue disorders and other conditions among patients with breast implants in comparison with other plastic surgery patients, according to various time parameters of initial implantation, southeastern United States, 1960–1996
Condition Age (years) at initial implantation Calendar year of initial implantation No. of years since initial implantation
<30 30–34 35–39 ≥40 <1975 1975–1979 1980–1984 ≥1985 <5 5–9 10–14 ≥15
Connective tissue disorders 2.3 (94)† 2.0 (89) 3.9‡ (83) 1.8‡ (85) 1.3 (40) 2.2‡ (119) 2.1‡ (125) 2.1‡ (67) 1.6 (61) 1.9‡ (125) 3.9‡ (101) 1.5 (64)
Rheumatoid arthritis 1.9 (68) 4.0 (63) 4.2‡ (68) 1.5‡ (59) 0.8 (27) 2.1‡ (100) 2.2‡ (86) 2.2‡ (45) 1.8 (43) 1.9‡ (91) 3.1‡ (74) 1.1 (50)
Scleroderma ∞ (3) 0.9 (7) ∞ (6) 3.3 (7) ∞ (2) 2.5 (4) 1.5 (11) ∞ (6) ∞ (4) 2.0 (13) ∞ (3) ∞ (3)
Systemic lupus 4.3 (28) 0.9 (20) 1.2 (6) 2.8‡ (18) ∞ (8) 3.9 (17) 2.8 (31) 1.2 (16) 1.2 (15) 1.6 (23) ∞ (25) ∞ (9)
Sjögren’s syndrome ∞ (9) ∞ (8) ∞ (12) 8.3‡ (14) 5.7 (5) ∞ (12) ∞ (16) 4.4 (10) ∞ (5) 5.5 (14) 8.3 (14) ∞ (10)
Other conditions
Other arthritis 1.8 (162) 1.4 (176) 1.5 (181) 1.2 (205) 2.3‡ (90) 1.4‡ (250) 1.2 (258) 1.2 (126) 1.6‡ (149) 1.0 (217) 1.4 (219) 1.8‡ (139)
Raynaud’s phenomenon 3.4 (37) 1.3 (20) 4.2 (24) 2.6 (16) ∞ (5) 2.5 (31) 1.5 (39) 10.8‡ (22) ∞ (27) 1.5 (32) 8.4‡ (28) 1.8 (10)
Fibromyalgia 1.3 (103) 1.0 (96) 1.3 (69) 1.4 (43) 3.4 (34) 1.3 (92) 1.0 (109) 1.7 (76) 1.0 (72) 1.3 (113) 1.2 (83) 3.5 (43)
Chronic fatigue syndrome 1.6 (97) 1.3 (59) 3.1 (47) 4.1‡ (43) ∞ (25) 1.5 (75) 1.7 (90) 4.4‡ (56) 2.4 (46) 1.9‡ (83) 1.7 (72) ∞ (45)
* Adjusted for age at follow-up (5-year intervals through age 85 years), calendar period of follow-up (1960–1964, …, 1990–1994, 1995–1996), and race (White or Black).
† Numbers in parentheses, number of breast implant patients with the disorder.
‡ 95% confidence interval excluded 1.0.
TABLE 4.
Results of two board-certified rheumatologists’ reviews of selected self-reports of rheumatoid arthritis, scleroderma, and Sjögren’s syndrome among patients with breast implants and other plastic surgery patients, southeastern United States, 1960–1996
Condition and rheumatologists’ assessment of diagnosis All patients Patients with breast implants Comparison patients
No. % No. % No. %
Rheumatoid arthritis (
n = 114)* (
n = 97) (
n = 17)
Likely 20 17.5 16 16.5 4 23.5
Unlikely 80 70.2 69 71.1 11 64.7
Unassessable 13 11.4 12 12.4 1 5.9
No consensus 1 0.9 0 0.0 1 5.9
Scleroderma (
n = 8) (
n = 7) (
n = 1)
Likely 2 25.0 2 28.6 0 0.0
Unlikely 2 25.0 2 28.6 0 0.0
Unassessable 4 50.0 3 42.9 1 100.0
Sjögren’s syndrome (
n = 20) (
n = 19) (
n = 1)
Likely 6 30.0 6 31.6 0 0.0
Unlikely 7 35.0 7 36.8 0 0.0
Unassessable 7 35.0 6 31.6 1 100.0
* Number of medical records that were reviewed by the rheumatologists. In standard chi-squared testing, none of the tests for differences produced significant results.
TABLE 5.
Projections of the likely number of cases of connective tissue disorders in the patient population based on the number of reported cases assessed by rheumatologists to represent “likely” diagnoses, southeastern United States, 1960–1996
Condition Reported no. of cases % for which medical record was obtained % for which diagnosis was assessed as “likely” No. of likely cases identified* Projected likely no. of cases†
Rheumatoid arthritis, scleroderma, or Sjögren’s syndrome
Implant patients 310 39.7 19.5 24 60
Comparison patients 54 35.2 21.0 4 11
Relative risk 2.2 2.5 2.0
95% confidence interval 1.6, 3.0 0.8, 7.8 0.7, 5.4
Rheumatoid arthritis only
Implant patients 258 37.6 16.5 16 43
Comparison patients 49 34.7 23.5 4 11
Relative risk 1.9 1.9 1.3
95% confidence interval 1.4, 2.7 0.6, 6.2 0.5, 3.8
* Derived by multiplying the reported number of cases by the percentage of records obtained and the percentage of obtained records with diagnoses assessed as likely.
† Derived by multiplying the reported number of cases by the percentage of obtained records with diagnoses assessed as likely.
References
1.
Brinton LA, Lubin JH, Burich MC, et al. Breast cancer following augmentation mammoplasty (United States).
Cancer Causes Control
2000
;
11
:
819
–27.
2.
Brinton LA, Lubin JH, Burich MC, et al. Cancer risk at sites other than the breast following augmentation mammoplasty.
Ann Epidemiol
2001
;
11
:
248
–56.
3.
McLaughlin JK, Nyren O, Blot WJ, et al. Cancer risk among women with cosmetic breast implants: a population-based cohort study in Sweden.
J Natl Cancer Inst
1998
;
90
:
156
–8.
4.
Mellemkjaer L, Kjoller K, Friis S, et al. Cancer occurrence after cosmetic breast implantation in Denmark.
Int J Cancer
2000
;
88
:
301
–6.
5.
Baldwin CM Jr, Kaplan EN. Silicone-induced human adjuvant disease?
Ann Plast Surg
1983
;
10
:
270
–3.
6.
Copeland M, Kressel A, Spiera H, et al. Systemic inflammatory disorder related to fibrous breast capsules after silicone implant removal.
Plast Reconstr Surg
1993
;
92
:
1179
–81.
7.
Fock KM, Feng PH, Tey BH. Autoimmune disease developing after augmentation mammoplasty: report of 3 cases.
J Rheumatol
1984
;
11
:
98
–100.
8.
Marik PE, Kark AL, Zambakides A. Scleroderma after silicone augmentation mammoplasty: a report of 2 cases.
S Afr Med J
1990
;
77
:
212
–13.
9.
Okano Y, Nishikai M, Sato A. Scleroderma, primary biliary cirrhosis, and Sjögren’s syndrome after cosmetic breast augmentation with silicone injection: a case report of possible human adjuvant disease.
Ann Rheum Dis
1984
;
43
:
520
–2.
10.
Sahn EE, Garen PD, Silver RM, et al. Scleroderma following augmentation mammoplasty: report of a case and review of the literature.
Arch Dermatol
1990
;
126
:
1198
–202.
11.
Sergott TJ, Limoli JP, Baldwin CM Jr, et al. Human adjuvant disease, possible autoimmune disease after silicone implantation: a review of the literature, case studies, and speculation for the future.
Plast Reconstr Surg
1986
;
78
:
104
–14.
12.
Spiera H, Kerr LD. Scleroderma following silicone implantation: a cumulative experience of 11 cases.
J Rheumatol
1993
;
20
:
958
–61.
13.
van Nunen SA, Gatenby PA, Basten A. Post-mammoplasty connective tissue disease.
Arthritis Rheum
1982
;
25
:
694
–7.
14.
Varga J, Schumacher HR, Jimenez SA. Systemic sclerosis after augmentation mammoplasty with silicone implants.
Ann Intern Med
1989
;
111
:
377
–83.
15.
Weiner SR, Paulus HE. Chronic arthropathy occurring after augmentation mammoplasty.
Plast Reconstr Surg
1986
;
77
:
185
–92.
16.
Burns CJ, Laing TJ, Gillespie BW, et al. The epidemiology of scleroderma among women: assessment of risk from exposure to silicone and silica.
J Rheumatol
1996
;
23
:
1904
–11.
17.
Edworthy SM, Martin L, Barr SG, et al. A clinical study of the relationship between silicone breast implants and connective tissue disease.
J Rheumatol
1998
;
25
:
254
–60.
18.
Englert H, Joyner E, McGill N, et al. Women’s health after plastic surgery.
Intern Med J
2001
;
31
:
77
–89.
19.
Gabriel SE, O’Fallon WM, Kurland LT, et al. Risk of connective-tissue diseases and other disorders after breast implantation.
N Engl J Med
1994
;
330
:
1697
–702.
20.
Giltay EJ, Bernelot Moens HJ, Riley AH, et al. Silicone breast prostheses and rheumatic symptoms: a retrospective follow up study.
Ann Rheum Dis
1994
;
53
:
194
–6.
21.
Goldman JA, Greenblatt J, Joines R, et al. Breast implants, rheumatoid arthritis, and connective tissue diseases in a clinical practice.
J Clin Epidemiol
1995
;
48
:
571
–82.
22.
Greenland S, Finkle WD. A retrospective cohort study of implanted medical devices and selected chronic diseases in Medicare claims data.
Ann Epidemiol
2000
;
10
:
205
–
This is a real article from scientific literature. You can skim it and then do to the end. It brings real statistics into the discussion. Hysteria is not science. Just becasue you think something happened to you or your family, blind studies and eval of data will not support it. People get diseases whether they have implants or not. It's whether they increase for those with implants vs those without. Does not appear to be so, scientifically.
![[banana]](https://res-5.cloudinary.com/rivals/image/upload/qo9fu1unj7ctwin1ayii.gif "banana [banana]")
